All is Not Butter that Comes from the Cow: The Bovine Viral Diarrhea. Understanding the Pathogenesis of Cytopathic and Non-Cytopathic Infection
نویسندگان
چکیده
منابع مشابه
Understanding the Pathogenesis of Cytopathic and Noncytopathic Bovine Viral Diarrhea Virus Infection Using Proteomics
Bovine Viral Diarrhea Virus (BVDV) is a single-stranded RNA virus in the Pestivirus genus within the Flaviviridae family. BVDV infections are seen in all ages and breeds of cattle worldwide and have significant economic impact due to productive and reproductive losses (Houe 2003). Two antigenically distinct genotypes of BVDV exist, type 1 and 2 (Ridpath et al. 1994). BVDV of both genotypes may ...
متن کاملCharacterization of the immune response of cattle against non-cytopathic and cytopathic biotypes of bovine viral diarrhoea virus.
Cross-infection studies of normal calves infected with homologous pairs of non-cytopathic and cytopathic bovine viral diarrhoea virus (BVDV) showed significant differences in both humoral and cell-mediated immune responses against either biotype over a period of 5 months. Serological assays after primary intranasal inoculation showed striking significant (P < 0.05) differences between biotypes....
متن کاملMonoclonal antibody analyses of cytopathic and noncytopathic viruses from fatal bovine viral diarrhea virus infections.
A panel of monoclonal antibodies that recognize the two major glycoproteins of bovine viral diarrhea virus (BDV) was used to evaluate the antigenic relationship between cytopathic (CP) and noncytopathic (NCP) viruses isolated from cattle dead or dying from fatal BDV infections. Various unrelated BDV isolates were initially screened by indirect immunofluorescence with monoclonal antibodies direc...
متن کاملRevisiting the concept of a cytopathic viral infection
The outcome of a viral infection with respect to cellular fate is a fundamental aspect of viral biology. Different virus families have vastly different interactions with their host cells, but they have long been broadly grouped as causing either persistent or cytopathic infections. Persistent infections are established through a variety of mechanisms, but all result in a long-term infection of ...
متن کاملDetection and characterization of genetic recombination in cytopathic type 2 bovine viral diarrhea viruses.
In cytopathic bovine viral diarrhea virus genotype 1 (BVDV1) isolates, insertions are reported at position A (amino acid [aa] 1535) and position B (aa 1589). Insertions at position B predominate. In this survey it was found that in BVDV2, insertions at position A predominate. Possible reasons for this difference in relative frequency are discussed.
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ژورنال
عنوان ژورنال: Journal of Ancient Diseases & Preventive Remedies
سال: 2015
ISSN: 2329-8731
DOI: 10.4172/2329-8731.1000126